Clinic News Latest in CardiologycompariSon of secOnd-generation seLf-expandable vs. balloon-expandable Valves and gEneral vs. local anaesthesia in Transcatheter Aortic Valve ImplantationThe goal of the SOLVE-TAVI trial was to compare the safety and efficacy of the Edwards Sapien S3 valve vs. Medtronic’s CoreValve among patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. Further, in a 2x2 factorial design, the trial also sought to compare conscious sedation vs. general anesthesia in this patient population.Immune Checkpoint Inhibitors and Venous ThromboembolismDoes an early rise in C-reactive protein (CRP) levels during immune checkpoint inhibitor (ICI) therapy predict the risk of venous thromboembolism (VTE) in cancer patients?Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction TherapyThe goal of the VALOR-HCM trial was to assess the safety and efficacy of adding mavacamten to maximally tolerated medical therapy among patients with obstructive hypertrophic cardiomyopathy (HCM).Papillary Muscle Structural Abnormalities and Site of Origin of ArrhythmiasDoes the finding of structural abnormalities on the papillary muscles have an association with site of origin of arrhythmias? Can multimodality imaging be of benefit in planning ablation procedures?A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and ObesityThe goal of the SUMMIT trial was to compare the safety and efficacy of tirzepatide among patients with heart failure with preserved ejection fraction (HFpEF) and obesity.Evaluation of Tricuspid Valve Percutaneous Repair System in the Treatment of Severe Secondary Tricuspid DisordersThe goal of the TRI.Fr trial was to assess the efficacy and safety of tricuspid transcatheter edge-to-edge repair (T-TEER) + optimized medical therapy (OMT) compared with OMT alone among patients with symptomatic ≥ severe tricuspid regurgitation (TR).Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis–Extended Antiplatelet MonotherapyThe goal of the HOST-EXAM trial was to assess the safety and efficacy of clopidogrel vs. aspirin monotherapy among patients who had completed the required duration of dual antiplatelet therapy (DAPT) therapy post–drug-eluting stent (DES) percutaneous coronary intervention (PCI).Chlorthalidone vs. Hydrochlorothiazide and Kidney OutcomesIs chlorthalidone superior to hydrochlorothiazide in preventing kidney outcomes when used for hypertension treatment?Cardiovascular Risk in Prostate Cancer: Key PointsThe following are key points to remember from a state-of-the-art review on cardiovascular (CV) risk in prostate cancer (PC).Congress Seeks Streamlined Continuing Resolution, ACC Advocacy Urges Lawmakers to Address Health Policy PrioritiesCongress must pass funding legislation by Dec. 20 to prevent a government shutdown. Although a continuing resolution (CR) proposed earlier this week included several important health care provisions, significant opposition due to the inclusion of many other policy add-ons have forced congressional leaders to pivot to developing a more streamlined CR.
